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Detection of circulating hybrid cells and circulating tumor cells in cerebrospinal fluid for leptomeningeal metastasis diagnosis and therapeutic prediction

PurposeLeptomeningeal metastasis (LM) represents a serious complication of advanced malignancies with poor prognosis. Conventional diagnostic approaches, such as MRI and cerebrospinal fluid (CSF) cytology lack sufficient sensitivity—particularly in early-stage disease or when imaging modalities are...

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Bibliografiset tiedot
Päätekijät: Yanting Liu, Jiaxin Liang, Min Zhang, Nianhua Cao, Jie Xue, Xiaodi Zhang, YongXu Jia, Zhiwei Chang, Guodong Zhang, Yan Li, Hongyan Hui, Ruijuan Fan, Kelei Zhao, Zongbin Liu, Guifang Zhang, Ping Lu, Yinghua Ji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2025-12-01
Sarja:Frontiers in Cell and Developmental Biology
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Linkit:https://www.frontiersin.org/articles/10.3389/fcell.2025.1716168/full
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