Induction and characterization of neoplastic bladder tumors in a transgenic porcine model

Background Large animal models of bladder cancer are lacking. Objective This study aimed to develop and characterize a transgenic porcine model of bladder cancer (BC) using Oncopigs expressing Cre-inducible KRAS G12D and TP53 R167H mutations. Methods Eleven female Oncopigs underwent tumor induction...

Full description

Bibliographic Details

Main Authors:	Andreas Aulitzky, Viranda H Jayalath, Abraham Meyerson, Sanaz Firouzi, Daniel V Rodriguez, Rebecca Dubrovsky, Laura Alvim, Caoimhe Ryan, Rand Wilcox Vanden Berg, Christopher Cheleuitte-Nieves, Alexandre Doudt, Lennert Eismann, Natasha Kudinova, Kwanghee Kim, Hikmat Al-Ahmadie, Sebastien Monette, Shahrokh F Shariat, Jonathan A Coleman
Format:	Artigo
Language:	Inglês
Published:	SAGE Publishing 2026-09-01
Series:	Bladder Cancer
Online Access:	https://doi.org/10.1177/23523735261439691
Tags:	Add Tag No Tags, Be the first to tag this record!