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Vaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2

<p>Abstract</p> <p>Background</p> <p>A dengue virus type 2 (DEN-2 Tonga/74) isolated from a 1974 epidemic was characterized by mild illness and belongs to the American genotype of DEN-2 viruses. To prepare a vaccine candidate, a previously described 30 nucleotide deletion (Δ30) in the 3' untranslate...

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Autores principales: Murphy Brian R, Hanley Kathryn A, Hanson Christopher T, Blaney Joseph E, Whitehead Stephen S
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2004-10-01
Colección:BMC Infectious Diseases
Acceso en línea:http://www.biomedcentral.com/1471-2334/4/39
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