Fibril core regions in engineered α-synuclein dimer are crucial for blocking of fibril elongation
Synucleinopathies like Parkinson's disease are neurodegenerative diseases which are associated with the deposition of fibrillar aggregates of the endogenous protein α-synuclein (α-syn). The inhibition of the elongation of α-syn fibrils is of great scientific interest and an option in the design of t...
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| Автори: | , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Elsevier
2023-01-01
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| Серія: | BBA Advances |
| Предмети: | |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S266716032300039X |
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