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From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients

Genetic histone variants have been implicated in cancer development and progression. Mutations affecting the histone 3 (H3) family, H3.1 (encoded by <i>HIST1H3B</i> and <i>HIST1H3C</i>) and H3.3 (encoded by <i>H3F3A</i>), are mainly associated with pediatric brain cancers. While considered poor prog...

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Kaydedildi:
Asıl Yazarlar: Benedicte Grebstad Tune, Heena Sareen, Branka Powter, Smadar Kahana-Edwin, Adam Cooper, Eng-Siew Koh, Cheok S. Lee, Joseph W. Po, Geoff McCowage, Mark Dexter, Lucy Cain, Geraldine O’Neill, Victoria Prior, Jonathan Karpelowsky, Maria Tsoli, Lars O. Baumbusch, David Ziegler, Tara L. Roberts, Paul DeSouza, Therese M. Becker, Yafeng Ma
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2023-10-01
Seri Bilgileri:Biomedicines
Konular:
childhood brain cancer
adult glioma
glioblastoma
circulating free DNA (cfDNA)
circulating tumor DNA (ctDNA)
histone mutations
Online Erişim:https://www.mdpi.com/2227-9059/11/11/2907
Etiketler: Etiketle
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