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High-resolution mapping of heteroduplex DNA formed during UV-induced and spontaneous mitotic recombination events in yeast

In yeast, DNA breaks are usually repaired by homologous recombination (HR). An early step for HR pathways is formation of a heteroduplex, in which a single-strand from the broken DNA molecule pairs with a strand derived from an intact DNA molecule. If the two strands of DNA are not identical, there...

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Autori principali: Yi Yin, Margaret Dominska, Eunice Yim, Thomas D Petes
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications Ltd 2017-07-01
Serie:eLife
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Accesso online:https://elifesciences.org/articles/28069
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