Development of an LC–MS/MS method for the quantitation of deoxyglycychloxazol in rat plasma and its application in pharmacokinetic study

Deoxyglycychloxazol (TY501) is a glycyrrhetinic acid derivative which exhibits high anti-inflammatory activity and reduced pseudoaldosteronism compared to glycyrrhetinic acid. In this study, a sensitive and rapid liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was established for th...

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Hlavní autoři:	Rongshan Li, Ruixue Ran, Quansheng Li, Yurong Huang, Yuan Gu, Duanyun Si
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2016-06-01
Edice:	Journal of Pharmaceutical Analysis
Témata:	Deoxyglycychloxazol (TY501) LC–MS/MS APCI Pharmacokinetics Rat plasma
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2095177916300090
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