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Misfolding linked mutations of SERPINA1 gene are uncommon in preeclampsia

Background: Alpha-1 antitrypsin (A1AT) is a protease inhibitor that plays an important role in regulating oxidative stress in preeclampsia (PE). Recent studies have shown that A1AT is misfolded in PE. However, the cause of A1AT misfolding is not known. Mutations in SERPINA1 gene is an established so...

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Autors principals: Chandrakala Nagarajappa, Sheela Shikaripur Rangappa, Sharath Balakrishna
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer Medknow Publications 2019-01-01
Col·lecció:Archives of Medicine and Health Sciences
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Accés en línia:http://www.amhsjournal.org/article.asp?issn=2321-4848;year=2019;volume=7;issue=2;spage=177;epage=180;aulast=Nagarajappa
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