Structural Dissection of the First Events Following Membrane Binding of the Islet Amyloid Polypeptide
The islet amyloid polypeptide (IAPP) is the main constituent of the amyloid fibrils found in the pancreas of type 2 diabetes patients. The aggregation of IAPP is known to cause cell death, where the cell membrane plays a dual role: being a catalyst of IAPP aggregation and being the target of IAPP to...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2022-03-01
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| Series: | Frontiers in Molecular Biosciences |
| Assuntos: | |
| Acceso en liña: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.849979/full |
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