Oxostephanine, Thalmiculine, and Thaliphyline—Three Isoquinoleine Alkaloids That Inhibit L-Type Voltage-Gated Ca²⁺ Channels

The isoquinoline alkaloids (IAs) represent a large and diverse subfamily of phytochemicals in terms of structures and pharmacological activities, including ion channel inhibition. Several IAs, such as liriodenine (an oxoaporphine) and curine (a bisbenzylisoquinoline (BBIQ), inhibit the L-type voltag...

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Autores principales:	Jacinthe Frangieh, Claire Legendre, Dimitri Bréard, Pascal Richomme, Daniel Henrion, Ziad Fajloun, César Mattei, Anne-Marie Le Ray, Christian Legros
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2022-06-01
Colección:	Future Pharmacology
Materias:	isoquinoline alkaloids L-type voltage-gated Ca<sup>2+</sup> channels intracellular Ca<sup>2+</sup> measurement Fura-2 fluorescent probe GH3b6 cells
Acceso en línea:	https://www.mdpi.com/2673-9879/2/3/16
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