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Thiram, an inhibitor of 11ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway

Abstract Background The anti-osteosarcoma effects of hydrocortisone and thiram, an inhibitor of type 2 11ß-hydroxysteroid dehydrogenase (11HSD2), have not been reported. The purpose of this study was to investigate the effects of hydrocortisone alone or the combination of hydrocortisone with thiram...

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Bibliografische gegevens
Hoofdauteurs: You Zhang, Nanjing Li, He Li, Maojia Chen, Wei Jiang, Wenhao Guo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2023-03-01
Reeks:BMC Pharmacology and Toxicology
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Online toegang:https://doi.org/10.1186/s40360-023-00655-0
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