Cardamonin inhibits the growth and stemness of osteosarcoma stem cells by inducing autophagy and inhibiting the Wnt/β-catenin signaling pathway

Abstract Cardamonin (CDN) has been shown to have promising anticancer effects against osteosarcoma (OS). Nevertheless, the molecular processes of it are still not well understood. Our investigation revealed that CDN has significant cytotoxic effects and diminishes cell viability in OS. The self-rene...

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Autors principals:	Lulu Zhang, Yu Jin, Qiannan Ding, Yulei Li, Lixia Yang, Mengyun Li, Zuo Lv, Kaifang Wang, Maowei Yang, Haixin Zhang, Xiucheng Li
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-08-01
Col·lecció:	Scientific Reports
Matèries:	Osteosarcoma Cardamom Cancer stem cell Autophagy Wnt/β-catenin signaling pathway
Accés en línia:	https://doi.org/10.1038/s41598-025-14209-3
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