Trametinib’s Transformative Role in BRAF-Mutated Multisystem Langerhans Cell Histiocytosis: A Case Report
Langerhans cell histiocytosis (LCH) is an inflammatory neoplasm, though rare, of myeloid origin, primarily driven by mutations in the MAPK pathway, most specifically BRAF. It is characterized by having a wide clinical spectrum, including lytic bone lesions, endocrinopathy, and multisystem disease. D...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Korean Society of Pediatric Hematology-Oncology
2025-10-01
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| Series: | Clinical Pediatric Hematology-Oncology |
| Assuntos: | |
| Acceso en liña: | http://www.cpho.or.kr/journal/view.html?doi=10.15264/cpho.2025.32.2.61 |
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