Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by insulin

Angiopoietin-like 4 (Angptl4) is a glucocorticoid receptor (GR) primary target gene in hepatocytes and adipocytes. It encodes a secreted protein that inhibits extracellular LPL and promotes adipocyte lipolysis. In Angptl4 null mice, glucocorticoid-induced adipocyte lipolysis and hepatic steatosis ar...

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Autors principals:	Taiyi Kuo, Tzu-Chieh Chen, Stephanie Yan, Fritz Foo, Cecilia Ching, Allison McQueen, Jen-Chywan Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2014-05-01
Col·lecció:	Journal of Lipid Research
Matèries:	glucocorticoid receptor forkhead box protein O1 chromatin immunoprecipitation glucocorticoid response element
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0022227520375106
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