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Senolysis of gemcitabine‐induced senescent human pancreatic cancer cells

Abstract Introduction Gemcitabine (GEM) is often used to treat pancreatic cancer. Many anti‐cancer drugs induce cancer cell death, but some cells survive after cell cycle arrest. Such a response to DNA damage is termed cellular senescence. Certain drugs, including the Bcl‐2‐family inhibitor ABT‐263,...

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Bibliografski detalji
Glavni autori: Mohammad Mahbubul Hoque, Yuichi Iida, Hitoshi Kotani, Mamoru Harada
Format: Artigo
Jezik:Inglês
Izdano: Wiley 2024-04-01
Serija:Cancer Reports
Teme:
Online pristup:https://doi.org/10.1002/cnr2.2075
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