Rotation Conformational Effects of Selected Cytotoxic Cardiac Glycosides on Their Interactions with Na⁺/K⁺-ATPase

Cardenolides are an important group of steroidal natural products and have been used successfully for the treatment of cardiovascular diseases by targeting Na⁺/K⁺-ATPase (NKA) and found more recently to show potential anticancer activity. Biological investigations indicate that...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Yulin Ren, Peirun Yang, Judith C. Gallucci, Can Wang, Xiaolin Cheng, Sijin Wu, A. Douglas Kinghorn
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2025-12-01
Цуврал:	Molecules
Нөхцлүүд:	cardenolides Na<sup>+</sup>/K<sup>+</sup>-ATPase docking profiles molecular targets rotation conformation
Онлайн хандалт:	https://www.mdpi.com/1420-3049/30/24/4815
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!