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Synthesis and Biological Evaluation of Triazolyl 13α-Estrone–Nucleoside Bioconjugates

2′-Deoxynucleoside conjugates of 13α-estrone were synthesized by applying the copper-catalyzed alkyne–azide click reaction (CuAAC). For the introduction of the azido group the 5′-position of the nucleosides and a propargyl ether functional group on the 3-hydroxy group of 13α-estrone were chosen. The...

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Bibliografiske detaljer
Principais autores: Brigitta Bodnár, Erzsébet Mernyák, János Wölfling, Gyula Schneider, Bianka Edina Herman, Mihály Szécsi, Izabella Sinka, István Zupkó, Zoltán Kupihár, Lajos Kovács
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2016-09-01
Serier:Molecules
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Online adgang:http://www.mdpi.com/1420-3049/21/9/1212
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