Synthesis and Biological Evaluation of Triazolyl 13α-Estrone–Nucleoside Bioconjugates
2′-Deoxynucleoside conjugates of 13α-estrone were synthesized by applying the copper-catalyzed alkyne–azide click reaction (CuAAC). For the introduction of the azido group the 5′-position of the nucleosides and a propargyl ether functional group on the 3-hydroxy group of 13α-estrone were chosen. The...
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| Principais autores: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI AG
2016-09-01
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| Serier: | Molecules |
| Fag: | |
| Online adgang: | http://www.mdpi.com/1420-3049/21/9/1212 |
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