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Adaptive Immunity and Pathogenesis of Diabetes: Insights Provided by the α4–Integrin Deficient NOD Mouse

Background: The spontaneously diabetic “non-obese diabetic” (NOD) mouse is a faithful model of human type-1 diabetes (T1D). Methods: Given the pivotal role of α4 integrin (CD49d) in other autoimmune diseases, we generated NOD mice with α4-deficient hematopoiesis (NOD.α4-/-) to study the role of α4 i...

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Egile Nagusiak: Salim Oulghazi, Sarah K. Wegner, Gabriele Spohn, Nina Müller, Sabine Harenkamp, Albrecht Stenzinger, Thalia Papayannopoulou, Halvard Bonig
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2020-12-01
Saila:Cells
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Sarrera elektronikoa:https://www.mdpi.com/2073-4409/9/12/2597
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