Involvement of BCR::ABL1 in laminin adhesion of Philadelphia chromosome‐positive  acute lymphoblastic leukemia through upregulation of integrin α6

Abstract Background Adhesion of cancer cells to extracellular matrix laminin through the integrin superfamily reportedly induces drug resistance. Heterodimers of integrin α6 (CD49f) with integrin β1 (CD29) or β4 (CD104) are major functional receptors for laminin. Higher CD49f expression is reportedl...

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Main Authors:	Kazuya Takahashi, Thao Thu Thi Nguyen, Atsushi Watanabe, Hiroki Sato, Kinuko Saito, Minori Tamai, Daisuke Harama, Shin Kasai, Koshi Akahane, Kumiko Goi, Keiko Kagami, Masako Abe, Chiaki Komatsu, Yasuhiro Maeda, Kanji Sugita, Takeshi Inukai
Format:	Artigo
Language:	Inglês
Published:	Wiley 2024-04-01
Series:	Cancer Reports
Subjects:	ALL CD49f imatinib integrin α6 Philadelphia chromosome
Online Access:	https://doi.org/10.1002/cnr2.2034
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