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Prevalence of UDP-glucuronosyltransferase polymorphisms (UGT1A6∗2, 1A7∗12, 1A8∗3, 1A9∗3, 2B7∗2, and 2B15∗2) in a

Glucuronidation is an important phase II pathway responsible for many endogenous substances and drug metabolism. The present work evaluated allele frequencies of certain UDP-glucuronosyl-transferases (UGT 1A6∗2, A7∗12, A8∗3, A9∗3, 2B7∗2, and 2B15∗2) in Saudi Arabians that could provide essential eth...

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Principais autores: Khalid M. Alkharfy, Basit L. Jan, Sibtain Afzal, Fahad I. Al-Jenoobi, Abdullah M. Al-Mohizea, Saleh Al-Muhsen, Rabih Halwani, Mohammad K. Parvez, Mohammed S. Al-Dosari
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2017-02-01
Serier:Saudi Pharmaceutical Journal
Fag:
Glucuronidation
UDP-glucuronosyltransferase
UGT1A
UGT2B
Saudi gene polymorphism
Online adgang:http://www.sciencedirect.com/science/article/pii/S1319016416300573
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