Evaluation and Comparison of the Inhibition Effect of Astragaloside IV and Aglycone Cycloastragenol on Various UDP-Glucuronosyltransferase (UGT) Isoforms

As one of the main active ingredients from Radix Astragali (RA), orally dosed astragaloside IV (AST) is easily transformed to sapogenin-cycloastragenol (CAG) by deglycosylation in the gastrointestinal tract. Because the potential adverse effects of AST and CAG remain unclear, the present study in th...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Ruixue Ran, Chunze Zhang, Rongshan Li, Bowei Chen, Weihua Zhang, Zhenying Zhao, Zhiwei Fu, Zuo Du, Xiaolang Du, Xiaolong Yang, Zhongze Fang
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2016-11-01
Cyfres:	Molecules
Pynciau:	astragaloside IV cycloastragenol UDP-glucuronosyltransferases (UGTs) herb–drug interactions
Mynediad Ar-lein:	http://www.mdpi.com/1420-3049/21/12/1616
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!