Enhanced Medial Prefrontal Cortex and Hippocampal Activity Improves Memory Generalization in APP/PS1 Mice: A Multimodal Animal MRI Study

Memory generalization allows individuals to extend previously learned movement patterns to similar environments, contributing to cognitive flexibility. In Alzheimer’s disease (AD), the disturbance of generalization is responsible for the deficits of episodic memory, causing patients with AD to forge...

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Autori principali:	Weilin Liu, Jianhong Li, Le Li, Yuhao Zhang, Minguang Yang, Shengxiang Liang, Long Li, Yaling Dai, Lewen Chen, Weiwei Jia, Xiaojun He, Huawei Lin, Jing Tao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2022-03-01
Serie:	Frontiers in Cellular Neuroscience
Soggetti:	Alzheimer’s disease cognitive training generalization functional activity neurochemical metabolism
Accesso online:	https://www.frontiersin.org/articles/10.3389/fncel.2022.848967/full
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