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Engineering more stable, selectable marker-free autoluminescent mycobacteria by one step.

In our previous study, we demonstrated that the use of the autoluminescent Mycobacterium tuberculosis as a reporter strain had the potential to drastically reduce the time, effort, animals and costs consumed in evaluation of the activities of drugs and vaccines in live mice. However, the strains wer...

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Autori principali: Feng Yang, Moses M Njire, Jia Liu, Tian Wu, Bangxing Wang, Tianzhou Liu, Yuanyuan Cao, Zhiyong Liu, Junting Wan, Zhengchao Tu, Yaoju Tan, Shouyong Tan, Tianyu Zhang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2015-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4356594?pdf=render
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