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Rapid, serial, non-invasive assessment of drug efficacy in mice with autoluminescent Mycobacterium ulcerans infection.

Buruli ulcer (BU) caused by Mycobacterium ulcerans is the world's third most common mycobacterial infection. There is no vaccine against BU and surgery is needed for patients with large ulcers. Although recent experience indicates combination chemotherapy with streptomycin and rifampin improves cure...

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Principais autores: Tianyu Zhang, Si-Yang Li, Paul J Converse, Jacques H Grosset, Eric L Nuermberger
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2013-01-01
叢編:PLoS Neglected Tropical Diseases
在線閱讀:http://europepmc.org/articles/PMC3868507?pdf=render
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