Inhibition of Glycine Re-Uptake: A Potential Approach for Treating Pain by Augmenting Glycine-Mediated Spinal Neurotransmission and Blunting Central Nociceptive Signaling

Among the myriad of cellular and molecular processes identified as contributing to pathological pain, disinhibition of spinal cord nociceptive signaling to higher cortical centers plays a critical role. Importantly, evidence suggests that impaired glycinergic neurotransmission develops in the dorsal...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолч:	Christopher L. Cioffi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2021-06-01
Цуврал:	Biomolecules
Нөхцлүүд:	glycine GABA glycine transporter (GlyT) glycine receptor (GlyR) nociceptor <i>N</i>-methyl-<span style="font-variant: small-caps">d</span>-aspartate (NMDA) receptor
Онлайн хандалт:	https://www.mdpi.com/2218-273X/11/6/864
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!