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Old Passengers as New Drivers: Chromosomal Passenger Proteins Engage in Translesion Synthesis

Survivin is known for its dual biological role in apoptosis inhibition and mitotic progression. In addition to its being part of the chromosomal passenger complex (CPC), recent findings suggest additional roles for Survivin in the DNA damage response, further contributing to therapy resistance. In t...

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Principais autores: Katharina Falke, Elisabeth Schröder, Stefanie Mosel, Cansu N. Yürük, Sophie Feldmann, Désirée Gül, Paul Stahl, Roland H. Stauber, Shirley K. Knauer
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-10-01
Serier:Cells
Fag:
Survivin
Aurora B kinase
DNA damage response
replication
translesion synthesis
Online adgang:https://www.mdpi.com/2073-4409/13/21/1804
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