Practical and Asymmetric Synthesis of Apremilast Using Ellman’s Sulfinamide as a Chiral Auxiliary
Herein, we described a new protocol for the asymmetric synthesis of apremilast using <i>tert</i>-butanesulfinamide as a chiral auxiliary. This synthetic route consisted of four steps starting from the commercially available 3-hydroxy-4-methoxybenzaldehyde, and apremilast was accordingly obtained in...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI AG
2021-09-01
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| Serier: | Molbank |
| Fag: | |
| Online adgang: | https://www.mdpi.com/1422-8599/2021/3/M1275 |
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