Practical and Asymmetric Synthesis of Apremilast Using Ellman’s Sulfinamide as a Chiral Auxiliary
Herein, we described a new protocol for the asymmetric synthesis of apremilast using <i>tert</i>-butanesulfinamide as a chiral auxiliary. This synthetic route consisted of four steps starting from the commercially available 3-hydroxy-4-methoxybenzaldehyde, and apremilast was accordingly obtained in...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2021-09-01
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| Colecção: | Molbank |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/1422-8599/2021/3/M1275 |
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