Enhanced phagocytosis associated with multinucleated microglia via Pyk2 inhibition in an acute β-amyloid infusion model

Abstract Multinucleated microglia have been observed in contexts associated with infection, inflammation, and aging. Though commonly linked to pathological conditions, the larger cell size of multinucleated microglia might enhance their phagocytic functions, potentially aiding in the clearance of br...

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מידע ביבליוגרפי

Principais autores:	Ji-Won Lee, Kaito Mizuno, Haruhisa Watanabe, In-Hee Lee, Takuya Tsumita, Kyoko Hida, Yasutaka Yawaka, Yoshimasa Kitagawa, Akira Hasebe, Tadahiro Iimura, Sek Won Kong
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2024-08-01
סדרה:	Journal of Neuroinflammation
נושאים:	Protein Tyrosine Kinase 2B Microglia Multinucleation Phagocytosis β-amyloid Alzheimer’s disease
גישה מקוונת:	https://doi.org/10.1186/s12974-024-03192-7
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