Enhanced phagocytosis associated with multinucleated microglia via Pyk2 inhibition in an acute β-amyloid infusion model

Abstract Multinucleated microglia have been observed in contexts associated with infection, inflammation, and aging. Though commonly linked to pathological conditions, the larger cell size of multinucleated microglia might enhance their phagocytic functions, potentially aiding in the clearance of br...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Ji-Won Lee, Kaito Mizuno, Haruhisa Watanabe, In-Hee Lee, Takuya Tsumita, Kyoko Hida, Yasutaka Yawaka, Yoshimasa Kitagawa, Akira Hasebe, Tadahiro Iimura, Sek Won Kong
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2024-08-01
Σειρά:	Journal of Neuroinflammation
Θέματα:	Protein Tyrosine Kinase 2B Microglia Multinucleation Phagocytosis β-amyloid Alzheimer’s disease
Διαθέσιμο Online:	https://doi.org/10.1186/s12974-024-03192-7
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