Targeting Checkpoint Receptors and Molecules for Therapeutic Modulation of Natural Killer Cells
Among the most promising therapeutic modalities for cancer treatment is the blockade of immune checkpoint pathways, which are frequently co-opted by tumors as a major mechanism of immune escape. CTLA-4 and PD-1 are the representative examples, and their blockade by therapeutic antibodies leads to en...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2018-09-01
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| Edice: | Frontiers in Immunology |
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| On-line přístup: | https://www.frontiersin.org/article/10.3389/fimmu.2018.02041/full |
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