Paraspeckles Are Associated with the Activation and Nuclear Localization of Unphosphorylated miR-34a

<b>Background/Objectives:</b> Canonical microRNAs possess a 5′ phosphate required for Argonaute binding and activity. However, prior work identified an unphosphorylated, inactive nuclear pool of the important radiation-responsive microRNA, miR-34, that is rapidly phosphorylated and activated in resp...

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Detalhes bibliográficos

Principais autores:	Graham H. Read, Kristen McGreevy, Hanny Issawi, Tiffany Yang, Cynthia Tsang, Ihsan A. Turk, Emily Rietdorf, Whitaker Cohn, David W. Salzman, Julian P. Whitelegge, Joanne B. Weidhaas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-03-01
coleção:	Non-Coding RNA
Assuntos:	radiation microRNA paraspeckle miR-34a
Acesso em linha:	https://www.mdpi.com/2311-553X/12/2/12
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