Co-targeting of specific epigenetic regulators in combination with CDC7 potently inhibit melanoma growth
Summary: Melanoma is a highly aggressive skin cancer that frequently metastasizes, but current therapies only benefit some patients. Here, we demonstrate that the serine/threonine kinase cell division cycle 7 (CDC7) is overexpressed in melanoma, and patients with higher expression have shorter survi...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2022-08-01
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| Edice: | iScience |
| Témata: | |
| On-line přístup: | http://www.sciencedirect.com/science/article/pii/S2589004222010240 |
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