The adhesion and migration of microglia to β-amyloid (Aβ) is decreased with aging and inhibited by Nogo/NgR pathway
Abstract Background Alzheimer’s disease is characterized by progressive accumulation of β-amyloid (Aβ)-containing amyloid plaques, and microglia play a critical role in internalization and degradation of Aβ. Our previous research confirmed that Nogo-66 binding to Nogo receptors (NgR) expressed on mi...
Na minha lista:
| Principais autores: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2018-07-01
|
| Serier: | Journal of Neuroinflammation |
| Fag: | |
| Online adgang: | http://link.springer.com/article/10.1186/s12974-018-1250-1 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|