Microglial deletion and inhibition alleviate behavior of post-traumatic stress disorder in mice

Abstract Background Alteration of immune status in the central nervous system (CNS) has been implicated in the development of post-traumatic stress disorder (PTSD). However, the nature of overall changes in brain immunocyte landscape in PTSD condition remains unclear. Methods We constructed a mouse...

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Váldodahkkit:	Shuoshuo Li, Yajin Liao, Yuan Dong, Xiaoheng Li, Jun Li, Yong Cheng, Jinbo Cheng, Zengqiang Yuan
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2021-01-01
Ráidu:	Journal of Neuroinflammation
Fáttát:	Mass cytometry Microglia Microglial depletion Microglial activation PTSD
Liŋkkat:	https://doi.org/10.1186/s12974-020-02069-9
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