acCRISPR: an activity-correction method for improving the accuracy of CRISPR screens
Abstract High throughput CRISPR screens are revolutionizing the way scientists unravel the genetic underpinnings of engineered and evolved phenotypes. One of the critical challenges in accurately assessing screening outcomes is accounting for the variability in sgRNA cutting efficiency. Poorly activ...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2023-06-01
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| coleção: | Communications Biology |
| Acesso em linha: | https://doi.org/10.1038/s42003-023-04996-8 |
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