The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps

Background: Nucleic acid binding proteins are frequently targeted as autoantigens in systemic lupus erythematosus (SLE) and other interferon (IFN)-linked rheumatic diseases. The AIM-like receptors (ALRs) are IFN-inducible innate sensors that form supramolecular assemblies along double-stranded (ds)D...

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Detalles Bibliográficos

Principais autores:	Brendan Antiochos, Daniela Trejo-Zambrano, Paride Fenaroli, Avi Rosenberg, Alan Baer, Archit Garg, Jungsan Sohn, Jessica Li, Michelle Petri, Daniel W Goldman, Christopher Mecoli, Livia Casciola-Rosen, Antony Rosen
Formato:	Artigo
Idioma:	Inglês
Publicado:	eLife Sciences Publications Ltd 2022-05-01
Series:	eLife
Assuntos:	autoimmunity autoantibodies neutrophil extracellular traps
Acceso en liña:	https://elifesciences.org/articles/72103
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