Broad-Spectrum Inhibitors against Class A, B, and C Type β-Lactamases to Block the Hydrolysis against Antibiotics: Kinetics and Structural Characterization

ABSTRACT The emergence of antibiotic resistance has led to a global crisis for the physician to handle infection control issues. All antibiotics, including colistin, have lost efficiency against emerging drug-resistant bacterial strains due to the production of metallo-β-lactamases (MBLs) and serine...

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Hauptverfasser:	Nabeela Farhat, Divya Gupta, Abid Ali, Yogesh Kumar, Farheen Akhtar, Senthilguru Kulanthaivel, Prashant Mishra, Feroz Khan, Asad U. Khan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2022-10-01
Schriftenreihe:	Microbiology Spectrum
Schlagworte:	antibiotic resistance MDR β-lactam antibiotic β-lactamases β-lactamase inhibitors NDM-1
Online-Zugang:	https://journals.asm.org/doi/10.1128/spectrum.00450-22
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