Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus

Abstract Background Vaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the inherent biophysical traits presented by an individual antigen of int...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Neil C. Dalvie, Joseph R. Brady, Laura E. Crowell, Mary Kate Tracey, Andrew M. Biedermann, Kawaljit Kaur, John M. Hickey, D. Lee Kristensen, Alexandra D. Bonnyman, Sergio A. Rodriguez-Aponte, Charles A. Whittaker, Marina Bok, Celina Vega, Tarit K. Mukhopadhyay, Sangeeta B. Joshi, David B. Volkin, Viviana Parreño, Kerry R. Love, J. Christopher Love
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2021-05-01
سلاسل:	Microbial Cell Factories
الموضوعات:	Pichia pastoris Subunit vaccine Quality by design Biomanufacturing
الوصول للمادة أونلاين:	https://doi.org/10.1186/s12934-021-01583-6
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!