Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis
Comprehensive analysis of human TDP-43 knockout cells revealed that TDP-43 regulates hundreds of transcripts and is critical for maintaining the homeostasis of multiple subcellular organelles. TDP-43 is an RNA-binding protein that forms cytoplasmic aggregates in multiple neurodegenerative diseases....
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Life Science Alliance LLC
2019-10-01
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| Serier: | Life Science Alliance |
| Online adgang: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201900358 |
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