Neuroimmune signaling mediates astrocytic nucleocytoplasmic disruptions and stress granule formation associated with TDP-43 pathology

Alterations in transactivating response region DNA-binding protein 43 (TDP-43) are prevalent in amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other neurological disorders. TDP-43 influences neuronal functions and might also affect glial cells. However, specific intracellula...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Constance Zhou, Evelyn J. Hardin, Till S. Zimmer, Stephanie Jackvony, Daniel Barnett, Noopur Khobrekar, Elisa Giacomelli, Lorenz Studer, Adam L. Orr, Anna G. Orr
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-07-01
Colecção:	Neurobiology of Disease
Assuntos:	Neurodegeneration TDP-43 Astrocytes Nuclear pore Neuroimmune signaling Stress granules
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S096999612500155X
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!