Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells
Abstract Background Celastrol, a triterpene compound derived from the traditional Chinese medicine Tripterygium wilfordii, has been reported to possess potential antitumor activity towards various malignancies. However, the effect of celastrol on glioma cells and the underlying molecular mechanisms...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2019-05-01
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| Colecção: | Journal of Experimental & Clinical Cancer Research |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13046-019-1173-4 |
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