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Polysaccharide specific monoclonal antibodies provide passive protection against intranasal challenge with Burkholderia pseudomallei.

Burkholderia pseudomallei is a Gram-negative bacillus that is the causative agent of melioidosis. The bacterium is inherently resistant to many antibiotics and mortality rates remain high in endemic areas. The lipopolysaccharide (LPS) and capsular polysaccharide (CPS) are two surface-associated anti...

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Библиографические подробности
Главные авторы: David P AuCoin, Dana E Reed, Nicole L Marlenee, Richard A Bowen, Peter Thorkildson, Barbara M Judy, Alfredo G Torres, Thomas R Kozel
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2012-01-01
Серии:PLoS ONE
Online-ссылка:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0035386&type=printable
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