Polysaccharide specific monoclonal antibodies provide passive protection against intranasal challenge with Burkholderia pseudomallei.

Burkholderia pseudomallei is a Gram-negative bacillus that is the causative agent of melioidosis. The bacterium is inherently resistant to many antibiotics and mortality rates remain high in endemic areas. The lipopolysaccharide (LPS) and capsular polysaccharide (CPS) are two surface-associated anti...

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Bibliografische Detailangaben

Hauptverfasser:	David P AuCoin, Dana E Reed, Nicole L Marlenee, Richard A Bowen, Peter Thorkildson, Barbara M Judy, Alfredo G Torres, Thomas R Kozel
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0035386&type=printable
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