α-Synuclein purification significantly impacts seed amplification assay performance and consistency
Abstract α-Synuclein seed amplification assays are a promising diagnostic tool for synucleinopathies such as Parkinson’s disease and multiple system atrophy. Standardized conditions are required to ensure a high degree of inter- and intra-laboratory reproducibility when performing these assays. A si...
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| Автори: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2025-11-01
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| Серія: | Acta Neuropathologica Communications |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s40478-025-02151-4 |
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