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Enzalutamide induces cytotoxicity in desmoplastic small round cell tumor independent of the androgen receptor

Abstract Desmoplastic Small Round Cell Tumor (DSRCT) is a rare, pediatric cancer caused by the EWSR1::WT1 fusion protein. DSRCT predominantly occurs in males, which comprise 80-90% of the patient population. While the reason for this male predominance remains unknown, one hypothesis is that the andr...

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Hlavní autoři: Justin W. Magrath, Ilon N. Goldberg, Danh D. Truong, Alifiani B. Hartono, Shruthi Sanjitha Sampath, Chandler E. Jackson, Anushka Ghosh, Derrick L. Cardin, Haitao Zhang, Joseph A. Ludwig, Sean B. Lee
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-04-01
Edice:Communications Biology
On-line přístup:https://doi.org/10.1038/s42003-024-06003-0
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