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Enzalutamide induces cytotoxicity in desmoplastic small round cell tumor independent of the androgen receptor

Abstract Desmoplastic Small Round Cell Tumor (DSRCT) is a rare, pediatric cancer caused by the EWSR1::WT1 fusion protein. DSRCT predominantly occurs in males, which comprise 80-90% of the patient population. While the reason for this male predominance remains unknown, one hypothesis is that the andr...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Justin W. Magrath, Ilon N. Goldberg, Danh D. Truong, Alifiani B. Hartono, Shruthi Sanjitha Sampath, Chandler E. Jackson, Anushka Ghosh, Derrick L. Cardin, Haitao Zhang, Joseph A. Ludwig, Sean B. Lee
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Portfolio 2024-04-01
Σειρά:Communications Biology
Διαθέσιμο Online:https://doi.org/10.1038/s42003-024-06003-0
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