Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.
DNA damage accumulates in genome DNA during the long life of neurons, thus DNA damage repair is indispensable to keep normal functions of neurons. We previously reported that Ku70, a critical molecule for DNA double strand break (DSB) repair, is involved in the pathology of Huntington's disease (HD)...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2011-01-01
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| Serija: | PLoS ONE |
| Online pristup: | http://europepmc.org/articles/PMC3210167?pdf=render |
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