Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.

DNA damage accumulates in genome DNA during the long life of neurons, thus DNA damage repair is indispensable to keep normal functions of neurons. We previously reported that Ku70, a critical molecule for DNA double strand break (DSB) repair, is involved in the pathology of Huntington's disease (HD)...

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Hlavní autoři:	Takuya Tamura, Masaki Sone, Takeshi Iwatsubo, Kazuhiko Tagawa, Erich E Wanker, Hitoshi Okazawa
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2011-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC3210167?pdf=render
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