TET knockout cells transit between pluripotent states and exhibit precocious germline entry
Abstract TET1, TET2 and TET3 are DNA demethylases with important roles in development and differentiation. To assess the contributions of TET proteins to cell function during early development, single and compound knockouts of Tet genes in mouse pluripotent embryonic stem cells (ESCs) were generated...
Sparad:
| Huvudupphov: | , , , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Springer Nature
2025-10-01
|
| Serie: | The EMBO Journal |
| Ämnen: | |
| Länkar: | https://doi.org/10.1038/s44318-025-00597-9 |
| Taggar: |
Inga taggar, Lägg till första taggen!
|